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KMID : 1037020140030020071
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Medical Lasers; Engineering, Basic Research, and Clinical Application
2014 Volume.3 No. 2 p.71 ~ p.74
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Implication of Margin of Glottic Cancer: Laser Surgery
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Cho Jae-Gu
Jung Jin-Ho
Park Min-Woo
Baek Seung-Kuk
Kwon Soon-Young
Jung Kwang-Yoon
Woo Jeong-Soo
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Abstract
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Background and Objectives: An involved resection margin in a head and neck malignant neoplasm is one of the most important factors affecting local recurrence. The aim of this study is to assess the clinical impact of resected margin status in laser surgery for glottic cancers on local recurrences and larynx preservation.
Materials and Methods: Sixty four patients of glottis cancer from January 1994 to December 2013 were included in this study. The records were evaluated for disease recurrence rate, follow up duration, additional treatment modality, and laryngeal preservation. Pathologic reports with resection margin status were reviewed in all cases. Resection margins were evaluated in anterior, posterior, superior, inferior, and deep directions.
Results: Local recurrence was not associated with positive mucosal margin. The number of positive margins was also not associated with local recurrence (p=0.24). Only deep margin status showed association with local recurrence (p<0.05). The laryngeal preservation rate was 97%. All patients who underwent salvage laryngectomy had a positive deep margin.
Conclusion: Unlike other studies, in this study, mucosal margin did not have a significant impact on clinical outcome in laser surgery for early glottic cancer. However, a deep margin should be carefully evaluated during surgery and more study is needed.
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KEYWORD
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Glottic cancer, Margin status, Laser surgery
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